We evaluated the behavioral responses of white-tailed deer (Odocoileus virginianus) to 4 colors of wildlife warning reflectors (red, white, blue-green, and amber) that are purported to reduce the incidence of deer–vehicle collisions. We observed white-tailed deer behaviors relative to roads before and after installation of wildlife warning reflectors using a forward-looking infrared camera during 90 observation nights. We concluded that wildlife warning reflectors were ineffective in changing deer behavior such that deer–vehicle collisions might be prevented.